PDA Exam 3

41 cards·by cieracam

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Polymorphs

Theobroma oil, chloramphenicol, cocoa butter

Crystalline or amorphous forms

Chlorthalidone

Wetting agent

SDS

Facilitated Diffusion

GLUT1

Active Transport

5-fluorouracil and cardiac glycosides

Efflux pump

p-glycoprotein

Receptor-mediated endocytosis

insulin, growth hormone, erythropoietin

Liquid-filled Capsules

Digoxin

Diluents

Sodium phenytoin with calcium sulfate dihydrate is bad, when replaced with lactose it has higher bioavailability

Solvents

water, alcohols, glycols, ketones, oils

Topical Preservatives

Phenyl mercuric nitrate and acetate, Thimerosal

Oral Preservatives

Ethyl alcohol, Propylene glycol, Glycerin, Benzyl alcohol, Benzoic acid, Methyl and propylparaben

Opthalmic Preservatives

Benzalkonium chloride, Cetylpyridinium chloride, Benzethonium chloride

Chelating Agents

Edetate disodium, EDTA

Antioxidants (aqueous)

Ascorbic acid, sodium bisulfate/metabisulfite

Antioxidants (oil)

BHA, propyl gallate

Buffers

Boric acid/ Sodium borate, Citric acid monohydrate/ sodium citrate dihydrate

PH-adjusting

Acetic acid, sodium bicarbonate

Tonicity adjusting

NaCl, sodium nitrate, dextrose

Viscosity increasing

Methylcellulose, carboxymethylcellulose, acacia

Sweeteners

Sucrose, sorbitol, mannitol, saccharin, aspartame

Scents

Methyl salicylate, rose

Ointment bases

White petrolatum, lanolin, eucerin

Suppository bases

cocoa butter, glycerinated gelatin, PEG

Diluents/Fillers

Starch, lactose, dicalcium phosphate, microcrystalline cellulose

Binders

polyvinylpyrrolidone, gelatin, acacia

Solubilizing Agents

Alcohols, sodium lauryl sulphate, cyclodextrin

Disintegrating Agents

starch, microcrystalline cellulose

Coating Agents

Film-Hydroxypropyl methylcellulose, Enteric-cellulose acetate phtalate

Antiadherents

Magnesium oxide, Talc

Suspending/Wetting

Surfactants (sodium lauryl sulphate)

Emulsifying Agents

Acacia, Tragacanth

Photolysis

Sodium nitoprusside

Dehydration

Prostaglandin-2, tetracycline

Hydration

Cyanocobalamin

Decarboxylation

p-aminosalicylic acid

Vaporization

Nitroglycerine

Divided powders

psyllium mucilloid, massengill powder packets

Eutectic mixture

acetylsalicylic acid with menthol or antipyrine with salol

Hydroscopic

phenobarbitol sodium, pilocarpine, CaCl

Efflorescent

use anhydrous salt, alum, citric acid, caffeine