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Mutation
notes on board
17 cards·by browncl4
Mutation=___
mistake
polypeptide=___
string of proteins
Define Mutation.
Change in DNA structure
Define Point Mutations.
Change at specific point on DNA
Mutagen examples:___,___,___
radiation, chemicals, viruses
What are two types of point mutations?
Frame Shift and Base Substitution
A Frame Shift Mutation is where a ________. (also usually___)
nucleotide is added or subtracted (fatal)
A Base Substitution is where a nucleotide is ____.
substituted for another
An example of Base Substitution is____.
Sickle Cell Anemia
Sickle Cell happens on _____of______.
6th amino acid of beta hemoglobin protein
Normal___-> Mutant___, Normal___-> Mutant___
...CTT...->...CAT..., ...GAA...->...GUA...
GAA____
Glutamic acid
GUA___
Valine
Sickle cell anemia are RBCs unable to _____ & because it's shape is "off" the cells get ___ &
____, etc.
carry O2 properly, caught & clog up in arteries
SS
normal
Ss
some sickle cell resistance to malaria
ss
serve sickle cell anemia