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MCAT bio ch.1 cell viruses & subviral particles
29 cards·by michaelamaclin
viruses may be as small
20nm or as large as 300nm
viruses
are composed of genetic material a protein coat and sometimes an envelope containing lipids
capsid
protein coat
host cell
viruses must express and replicate genetic info within a ? cuz they lack ribosomes to carry out
protein synthesis
virions
after hijacking a cells machinery a virus will replicate and produce viral progeny which can
be released to infect additional cells
bacteriophages
are viruses that specifically target bacteria they do not actually enter bacteria they
simply inject their genetic material leaving the rema
tail sheath
can act like a syringe injecting genetic material into a bacterium
tail fibers
help bacteriophage to recognize and connect to the correct host cell
positive sense
the genome may be directly translated to functional proteins by the ribosomes of the host cell
negative sense
these viruses require synthesis of an RNA strand
retroviruses
are enveloped single stranded RNA viruses
reverse transcriptase
synthesizes DNA from single stranded RNA
step 1 of infection
virus has to bind to specific receptors on the host cell
step 2 of infection
the virus and the cell are brought into close enough proximity to permit additional
interactions
step 3 of infection
diff portions of the virion will be inserted into the host cell or only insert their genetic
material leaving their capsids outside the host
step 4 of infection
DNA viruses must go to the nucleus in order to be transcribed to mRNA
step 5 of infection
mRNA goes to the cytoplasm where it is translated to proteins
step 6 of infection
genetic material from positive sense RNA viruses stay in the cytoplasm where it is directly
translated to protein by host cell ribosomes
step 7 of infection
negative sense RNA viruses require RNA replicase which can then be translated to form
proteins
step 8 of infection
using the ribosomes tRNA amino acids and an enzymes of the host cell the viral RNA is translated
into protein
step 9 of infection
once the viral genome has been replicated it can be packaged within the capsid, the viral
genome must be returned to its original form befor
viral progeny
the host cell may no longer use the cell to carry out its life cycle
extrusion
a virus can leave the cell by fusing with its plasma membrane
lytic cycle
the bacteriophage makes maximal use of the cells machinery w/little regard for the survival
of the host cell
virulent
once the host is swollen w/new virions the cell lyses and other bacteria can be infected
provirus prophage
if the virus does not lyse the bacterium it may integrate into the host genome
lysogenic cycle
the virus will be replicated as the bacterium reproduces cuz it is now a part of the hosts genome
prions
are infectious proteins and are also nonliving things, can cause disease by triggering
misfolding of other proteins
viroids
small pathogens consisting of a very short circular single stranded RNA that infect plants
can cause metabolic and structural derangements i