Blood

In the _________, it functions in aiding respiratory sytem(O2+CO2 transport)

In the circulatory system also functions in____(digestive system)

In the _____ system, it functions in excretion,homeostasis,regulation of body temp.

Finally, the circulatory system functions in___.

How many liters of whole blood are in a man 70 kg (155lb.)?

In the whole blood there are three components that make them up, what are they?

___ are non-cellular and pH is neutral 7.35-7.45.

_____varies in pH levels which lead tometabolic problems with protein, ions, enzymes, antibodies and hormones.

In cells there's____(erythrocytes)

In cells there's____(leukocytes)

____ is 91-92% of water

In cells there's___(thrombocytes)

___ is % of solids in blood, mostly cells

In a test tube there's 1% white coat and ~45%___

In blood plasma there's blood plasma proteins such as_____,___,___.

In___ 60% is produced by the liver.

In ____36% is produced mostly by liver.

____ is osmotic pressure and also control direct effect on blood volume.

In_____high BP= cut out of salts and soon enough you'll need a water pill which transport ions, drugs & hormones.

In ___ there are alpha, beta and gamma.

_____transport lipids and fats.

_____soluble vitamins (A,D,C,K)

What are the two types of WBCs?

______ are 70% of WBCs

____ are composed of Neutrophils, Eosinophils and Basophils

Granulocytes are composed of 15-60% of ___, which fight bacterial infections

Granulocytes are composed of > 1% of ___hepanin and histamine,which promote inflammation and inhibit blood clotting

____ are composed of monocytes and lymphocytes

Agranulocytes are composed of 3-9%____ which become macrophages

What are the three irregularities/diseases of WBC Counts?

____has greater than 10,000/mm3 leukocytes

____has less than 5,000/mm3 of leukocytes

__ have granular cytoplasm in a drop of blood.

____ are platlets, in btwn RBC & WBC formed from megakarycytes

___are non nucleated and repair damage of blood vessels

There's are a few more____ in male than female

Main function of RBC and carrying oxygen through body depends on the amount of____.

1/3 by volume of RBCs are ____

_____ release oxygen, is darker and cyanosis from hypoxia.

____ is a defincency of RBC or hemoglobin where you can't carry enough oxygen properly to body for metabolism

Nutritional, Hemorrhagic, Aplastic, Pernicious, Hemolytic and Sickle Cell are all the different types of ________.

____ is not enough iron in diet.

____is excess bleeding internally or externally and not creating enough RBC.

_____ is where parasites and cemotherapy effects RBC production.

In aplastic anemia,____is where there's not enough RBC and oxygen being produced

____ is where there's not enough astrinsic factor, can't absorb enough vitamin B12 for proper RBC function.

During___RBC rupture.

The problem with_____ is that not enough RBC work fast enough for oxygen to work properly.

______is from parasitic and drug reaction

____ is another type of anemia that's a defective gene and harder to correct

______is a aggregated deoxyhemoglobin at low PO2 from decreased pH of RBC

People with____ are more resistant to malaria.

_____is known as Erythropoiesis

In____,there are 2.5 million ___produced per sec.

Where are new RBC being produced?

Bones in skull, pelvis, vertebrae, sternum are producing alot if____.

____ bone is found in ends of long bone such as femur, radius, ulna, humerus, all areas at epithelial end

_____ is a stem cell that allows RBC or WBC to be driven out of Red Bone marrow.

_____follow a pathway to create a leukocyte, create RBC or to carry thrombocyte structures

_____form a erythroblast

_____has a nucleus,replicate,reproduce, form mitosis erythrocyte (RBC)

_____is a hormone that controls RBC formation

_____monitored by liver and kidneys when oxygen concentrations drop and when PO2 drops to low

____stimulates erythropoietin

____ get red marrow, which increases the rate of erythroblasts being formed

Once erthroblasts rate increases, then they create more__, increasing oxygen carrying capacity that are eventually shut down through___.

_____stop bleeding

What are the three parts to Hemostatis?

_____is a cut blood vessel and smooth muscle around these vessels constrict rapidly

In ____, cells and platlets around this area start to release a neurotransmitter called sertonin

___ causes an even greater spasm of smooth muscle in an area that's damaged

During_______,which is rapid reaction and first blood vessel is damaged,erythrocytescomethrough and spasm occurs.

Second in _______after spasm occurs, shut things down, Platlets start to come in contact with damaged ends of vessel

Then finally in____after we contact damaged ends, ends start to stick together and all exposed collagen of RBCs form a platelet plug

If damage is not too severe the ____maybe enough to stop bleeding (hemostatis)

____is the last line of defense which is a stronger plug, using a protein that's soluble that becomes insoluble after damage.

____form a strong sticky insoluble fiber called fibrin

______is the final pathway where blood clot is formed.

______does not require platelets.

____starts at tissue damage,release tissue thromboplastin(factor III), release Ca+ and cause prothrombin activator to get blood clot.

____is blood clotting that occurs in the tissue or skin; bruise.

____blood clotting occurs in intact blood vessel, that can exceed blood flow.

_______occurs in intrinsic clotting mechanism.

____can be promblematic if repeat blood flow, and oxygen flow farther down.

Clavitis in lower leg are blood clots from ____ in blood vessels

____breaks off wall of blood vessel and travels through the whole circulatory system, which can be problematic b/c could lodge farther down

During____ thrombus lodges in a blood vessel in brain or heart, causing heart attack or stroke

During_____thrombus becomes dislodged and moves through circulation

_________(plasmin)

______turns into plasmin.

_____eats up clot

What is a active protein that breaks up clot?

In the_____ of inhibiting blood clot formation there's endothelium(thin layer of epipthelial cells).

A way to inhibit a blood clotting is to have a ___pathway to go through

_____prevents activation of intrinsic blood clot.

In inhibiting blood clotting______have prostacyclin that repel platelets so they don't stick to blood vessel wall.

_____is a transfusion reaction,where RBC react with antigens and cause blood to clump together

In inhibiting blood clot formation_______where thrombin stick and stay with fibrin threads once their formed

In inhibiting blood clot formation____which are combatted by alpha globulin proteins produced by liver

In inhibiting whole blood clot formation_____have basophils and mast cells to do this

_____major anticoagulin, have mast cells produced in lungs and liver and interferes with forming prothrombin activator

_______is lack of specific clotting factor causes bleeding

In inhibiting blood clotting______ is red-green color blindness, recessive x-linked traits and keep blood clotting to aminimum.

_____are specific proteins in blood plasma that work against antigens

An individual with type A with type A antigens that is not type A and have antigens against type A, what happens to blood?

______ have type A antigens and anti-B antibodies and it's ideal tranfusion is type A blood

____have neither antigens and produce anti-A and anti-B antibodies

During the ABO system_____person never seen a type B antigen, they still use antibodies against type B, spontaneous a few months after birth

Type AB (rarest blood type) is the_________.

If type AB has A-antigens that could react with type B anti-A bodies if type B is donated to AB causing a slight problem called the___

Why can't we give someone that is type AB, type O blood?

Rh is either on_ or not

___rarest blood type

___is 85% of population

____(D Immune Globulin)

If your Rh- and never come in contact with Rh+ & antigen you_____antibody

Rh+(father) x Rh-(mother)=Possibility of ___ baby

In ____mother gets antibodies circling her system to Rh factor,which crosses barrier,protecting developing fetus.

developing fetus produces___.

If mother is ____ and baby is Rh-, baby should be fine if mother hasn't produced any antibodies, which is found in ___.

____ is gamma-globulin immune serum containing Rh antibodies

____counters or neutralizes Rh Factor

____inactivates the Rh antigen in the fetus

During____mother's body can't become synthesized, so pregnancy's not an issue