PDA: Drugs for Crohn's Disease

Crohn's Disease drug names and their functions, mechanisms and side effects

3 cards·by lizzieheinonen

drug actionpharmacologymedicinecrohn's diseasedrugs

Azathioprine

inhibits DNA synthesis, an imidazolyl derivative, halts DNA replication & blocks purine synthesis pathway, affects proliferating cells(T )

Infliximab

neutralises TNF-alpha activity, "purified, recombinant DNA-derived chimeric human-mouse IgG monoclonal antibody", can also lyse inflam. cell

Methotrexate (Amethopterin)

Folate antagonist (inhibits DNA synthesis), prevents purine/pyramidine synthesis, SE: acute pneumonitis