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BIBB 270
9 cards·by jlakin
Neuropharmacology
concerned with drug induced changes in the functioning of cells in the NS.
Psychopharmacology
emphasizes drug-induced changes in mood, thinking, and behavior
Neuropsychopharmacology
understanding the neurobiology of behavior. Utilizing chemical agents as probes or to alter
behavior that is disturbed
Pharmacokinetcs
From dose administered to effect (bioavailability in the tissue)
RABIE
Routes of administration, Absorption and Distribution, Binding,
Inactivation-biotransformation-metabolism, andExcretion
Routes of drug administration
Drugs can be ingested, smoked, sniffed, inhaled,
takentransdermally,sublingually,rectally or injected (to the vein, muscle or under the
skin)
Absorption
The transfer of drugs through membrane in order to reach the blood stream (target: the brain).
Bioavailability
fraction of unchanged drug that reaches the systemic circulation.
First Pass metabolism
metabolism that occurs before the drug reaches systemic circulation. Significant for oral
and muscular routes of administration.