CSB331-Final Exam

Under the control of Notch transcription factor/induces Eph4A

forms dermis of back

forms all of the body's skeletal muscle cells

forms cartilage of ribs and vertebrae

closer to the neural tube

farther from the neural tube

TF, expressed by abaxial dermamyotome

TF, expressed by primaxial dermamyotome, induce the expression of other MRF(muscle reg factors)

expressed by migrating limb abaxial cells, receptor for scatter factor, controlled by Pax3

expressed by migrating limb abaxial cells, controlled by Pax3

a chemoattractant, binds to c-met

a multinucleated cell formed from a fused cell

muscle specific MMPs

muscle specific prot, binds to and stabilizes phospholopids

binds to and stabilized phospholipds

inc (muscle) fibers

larger (muscle) fibers

the star of satellite cells, promotes survival

Muscle TF, induce the expression of other MRF(muscle reg factors)

depositing matrix on free surfaces

spongy bone

space in the bone that is occupied by osteocytes

proccesses(with gap junctions) connecting the osteocytes

an important proteogylcan in collogen

a signature chondrocyte transcription factor

a TF. one of the master regulators of turning a fibroblasts into an osteogenic phenotype over a chondrogenic pheno

see L 17

bone creations that relies on a cartilage template

mesenchyme tissues is directly conveted into bone (Ihh-->Wnt-->Runx2--->osteoblast)

secreted by osteoblasts, regulates bone resorption/formation, binds the RANKL on osteoblasts,

precursors for endothelial and hematopoetic cells

attract pericytes to the vasculature by binding to Tie2 on pericytes

Hypoxia Inducing Factor, stimulates VEGF expression, degraded under high [O2]

hypoxia response element

a receptor on hemateopoeitic stem cell that binds to a BMSC ligand, this promotes survival/proliferation/stem cell character

produces platlets

thin walled blood vessel, were blood cells enter circulation

movement or passage of through intact capilary walls and into surrounding tissue

TM receptors that bind sugars

one of the ligands of selectin

integrin expressed by neutraphils, binds ICAM-1

cytokine produced by macrophages, caused alphaLbeta2 activation

activate aplhaLbeta2 in response to activation of the IL-8 receptor

another counter receptor bound by alphaLbeta2

secreted by the floor plate, attracts commissural neurons

binds to netrin

BMSC

receptor on monocytes, its activation stimulates differntiation into osteoblasts

ligand for RANK

inhibits prenylation-->inhibits osteoclast activity

unregulated on endothelial cells in response to inflammatory response

lymphocyte function associate antigen-1 (alphaLbeta2)

an endosomal sorting receptor

co-activator of b-cat (involved in causing activating genes in response to Wnt signalling)

interacts with ephrin and eph, cleaves E-cad

a genetic disorder, involves a mutation in APC, which is involved in degrading beta-cad

multinucleate cells the will form myofibers

what make muscle fibers. we are born with our adult number of myofibers

associated with Robo3 mutations

The movement or passage of blood cells, especially white blood cells, through intact capillary walls into surrounding body tissue.