PATHO-Skeletal

Dermato vs Polymyo --ADULT

Dermato vs Polymyo-- HELIOTROPE RASH

Dermato vs Polymyo-- GOTTRON PAPULES

Dermato vs Polymyo-- PERIMYSIAL (CD4+)

Dermato vs Polymyo-- ENDOMYOSIAL (CD8+)

Dusky red patches over knuckles, knees and elbows

Periorbital iliac discoloration

Defect on the deletion of the X Chromosome

Defect in the Mutation of dystrophin on the X Chromosome

Pseudohypertrophy of lower leg extremities (replaced by fat)

Absent imunnostaining for dystrophin

NF-2 Mutation

NF-1 MUTATION

Palisading Nuclei with Verocay bodies

"Schredded carrot" - Collagen bundles

Cafe au lait spots

Chromosome 17 (NF-1 or 2)

Chromosome 22 (NF- 1 or 2)